MRI Study of Subconjunctival and Intravitreal Injections

Preclinical PET Study of Intravitreal Injections.

Purpose This work aimed at describing the time course of vitreous clearance through the use of positron emission tomography (PET) as a noninvasive tool for pharmacokinetic studies of intravitreal injection. Methods The pharmacokinetic profile of intravitreal injections of molecules labeled with 18Fluorine (18F) was evaluated in adult Sprague Dawley rats by using a dedicated small-animal PET/c...

Intravitreal Injections

Man’s invasion into the sacred inner space of the eyethe vitreous cavity began around the same time he was attempting to invade the outer space i.e. in the 1950s. Von Sallman in1944 demonstrated the efficacy of Intravitreal antibiotics in a study in which he successfully cured endophthalmitis in rabbits by Intravitreal Penicillin injection. And thus began the era of Intravitreal antibiotics. Fi...

[Management of intravitreal injections].

PURPOSE The intravitreal injection is a minimally invasive technique which has been proved to be an effective therapy in the management of numerous vitreoretinal diseases. Its use has been rapidly increased in the last few years due to new medications and indications. However, non-standardized performance of this procedure might cause severe complications, being of special concern intraocular i...

The Success of Intravitreal Injections

Comparison of topical and subconjunctival anesthesia in intravitreal injection administrations.

PURPOSE To compare the effectiveness of topical and subconjunctival anesthesia in intravitreal injection administrations. METHODS Twenty-eight patients from a university clinic with bilateral diabetic macular edema were prospectively randomized to receive intravitreal injection of 4 mg triamcinolone under topical anesthesia for one eye and subconjunctival anesthesia for the other eye by using...